“They of course used the variola vaccination program which replaced the
looks like you are missing some text there after “replaced the” !
As for “slower rate of mutation a chance to mutate” : smallpox is believed to have been around since 3rd Century BC, and maybe even 7 centuries before that. Apologies : I don’t have formal evidence for 10th Century BC (why I’m saying “maybe”). Good quality peer reviewed studies for 22 centuries (plus) ago are rare
There is no reason to believe that dairymaids (back then) who had had cowpox didn’t develop the immunity Jenner later characterised : so there would have been some selective pressure for smallpox to mutate its vaccine target even then.
Variolation was used in the Far East (1549) even before it started to be used in the West in the 1720’s : that is some 428 years of further increased selective pressure to mutate the vaccine target, (250 years if you want to say “both East & West”)
Jenner started using vaccinia around 1796, but only published his paper on cowpox / vaccinia (from which the term vaccination is derived) in 1798. At least 179 years of even greater selective pressure yet still no mutation of the vaccine target.....
“Ahh, but those aren’t modern vaccines!” I hear you cry.... Well there was gradual improvement in the vaccines but there was a major step (freeze dried, heat-stable vaccine) in the 1950’s (25 years of yet further increased selective pressure)
So, with 22 centuries in which to mutate the vaccine target, 300 million deaths in the 20th century, and 15 million cases a year as late as 1967. Not a shred of evidence that there was a single mutation of the vaccine target...... that isn’t “slow”.
that is zero.
The OP was clamped for having an untaxed car on the highway , clamp removal fee + tax from the first of the month . And the second fine is the late licencing penalty of £80 and back tax from when the first 12 months ran out to when the tax was renewed .
Hey guys, sorry for going silent. I had to take a break from trying to deal with all this. I’m still upset about losing my father. I’m writing to his creditors and arguing with them and requesting settlement figures. My question is, isn’t there supposed to be some legislation where creditors should notice you’re not paying off more than the interest they’re charging and stop the account/stop your credit? I want to argue with them that they shouldn’t have allowed his credit cards to get into that state and propose as the majority of the balance is interest to write a lot off.
Shocking pictures reveal ‘disgusting’ conditions inside Hermes depot where workers ‘feel like slaves’. Read more at https://www.consumeractiongroup.co.uk/topic/419726-shocking-pictures-reveal-%E2%80%98disgusting%E2%80%99-conditions-inside-hermes-depot-where-workers-%E2%80%98feel-like-slaves%E2%80%99/
Euro Car Parks issued this ticket to the police in Devon and Cornwall. Read more at https://www.consumeractiongroup.co.uk/topic/419522-can-anyone-identify-the-parking-company-which-issued-this-ticket-to-the-police-in-devon-and-cornwall/